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During the Middle Ages, Italy was divided in small provinces that were in a permanent and endemic state of war. The renowned pope Hildegard (Gregory XII) and his successors tried to maintain a degree of peace in the Italian peninsula. Along with the increasing magnifiscense of garments and jewelry, the use of perfume escalated in their courts. Thus, the 16th century was the privileged era for perfumers. Potions, makeup, and hair grooming products enjoyed great popularity among Renaissance Ladies.

With the discovery of th3e Americas and its botanical species, ancient perfume formulas were considerably modified. Perfumers had brand new palette ingredients such as cocoa, vanilla, etc. In the same period, Spain, recently liberated from Arab domination, discovered the Oriental secrets for preparation of floral essence. It was also during this time that eliminating a rival by the use of poison became an art form. In addition to opiates, these Machiavellian masters used perfumes and cosmetics as vehicles to administer toxins. The Italian Renaissance commonly used hair products, in keeping with Roman tradition.

Venice in particular had a famous “water” that given the patrician ladies of this city the famous “ardent blonde,” reflected in the Veronese masterpiece. Perfume was also used to scent the homes and villas of the rich and famous, and was applied to objects such as jewels, fans, masques, and even birds and dogs. Traces of the enjoyment for perfume appear in many writings from this period. Books on perfumery were produced and indicate that perfume was an integral part of the way of life.

The extended use of perfume during this era of great discoveries even applied to the medical profession. Surgeons would treat wounds by applying aromatized wines and perfumed lotions

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